If you’re struggling to find remedies for treatment-resistant depression, Gianan Health is here to help. Esketamine (also known as Spravato), is an in-office treatment offering solutions for those who may have exhausted all other options.
What is Esketamine?
Esketamine (also known as Spravato) is a prescription medicine, also known as Esketamine, used primarily in the treatment of depression, particularly for patients who have not responded to traditional antidepressants. At Gianan Health, Spravato is administered as a nasal spray, usually in conjunction with an oral antidepressant.
Spravato works by targeting and modulating the brain’s glutamate system, which is thought to play a role in mood regulation. This mechanism is different from that of typical oral antidepressants, which often focus on neurotransmitters like serotonin and norepinephrine. By acting on glutamate, Spravato can provide rapid relief from depressive symptoms, sometimes within hours, which is a significant advantage for patients experiencing severe or treatment-resistant depression.
Treatment Session:
During a clinic visit, patients receive Spravato under the supervision of our healthcare providers. The treatment involves a monitoring period after administration to observe any immediate side effects or reactions. This careful supervision ensures the safety and efficacy of the medication. Spravato is usually part of a comprehensive treatment plan that includes psychotherapy and other supportive measures.
Patients might experience side effects such as dizziness, dissociation, or nausea, but these are typically managed with close monitoring and supportive care. Overall, Spravato offers a promising option for individuals struggling with depression who have not found relief from conventional treatments.
Who:
Spravato (Esketamine) is generally considered for patients who meet specific criteria. Here’s an overview of who might be a candidate for Spravato treatment:
- Treatment-Resistant Depression: Spravato is primarily used for individuals with major depressive disorder (MDD) who have not responded adequately to at least two different classes of antidepressant medications. This is often referred to as “treatment-resistant depression.”
- Diagnosis of Major Depressive Disorder: Candidates typically have a diagnosis of major depressive disorder. Spravato is not approved for other forms of depression or mood disorders.
- Failure of Conventional Therapies: Patients who have tried multiple conventional antidepressants (such as SSRIs or SNRIs) without significant improvement might be considered. Spravato is usually reserved for those who have not achieved sufficient relief with standard treatments.
- Comprehensive Treatment Plan: Spravato is used as part of a broader treatment plan that includes other therapeutic options like psychotherapy and oral antidepressants. It’s not meant to be a standalone treatment but rather a component of a comprehensive approach.
- Safety and Monitoring: Because Spravato can have side effects and requires careful monitoring, candidates need to be willing and able to comply with the clinic’s monitoring protocols. This includes a supervised administration and post-administration observation period to ensure safety.
- Informed Consent: Patients must be able to understand and consent to the treatment, including the potential side effects and the monitoring process.
We are happy to answer any questions and determined to find the right treatment plan for you. Contact us today.
How We Use Esketamine Treatment for Depression to Support Rapid Relief
At Gianan Health, we care deeply about helping individuals move forward when they feel stuck in the cycle of depression. We recognize how difficult it can be when symptoms persist despite trying different treatments. That’s why we offer Esketamine treatment for depression—an approach that brings relief to individuals who haven’t found results through conventional medication.
Our goal is to help bring relief faster and more safely through a process grounded in science, compassion, and consistency.
What Is a Spravato Treatment?
Spravato (esketamine) is a prescription nasal spray designed for adults living with treatment-resistant depression. Unlike traditional antidepressants, it works by acting on the brain’s glutamate system, opening new pathways to restore emotional balance.
Spravato is administered in a controlled, clinical environment, offering support and monitoring every step of the way. For those who haven’t found relief with other treatments, it can provide noticeable improvement within hours to days, creating new possibilities for healing and renewed hope.
Our Approach to Spravato Treatment for Depression Care
We focus on providing care that is responsive, structured, and rooted in each person’s needs. No two people experience depression in the same way, and we take time to understand each individual’s journey.
When we recommend Spravato for depression, it’s always part of a broader plan. We work together with you to create that plan, which can also include oral antidepressants, talk therapy, and check-ins designed to track progress over time. We want people to feel seen, heard, and supported throughout treatment.
What Esketamine Is—and Why We Use It
Esketamine for depression is a nasal spray medication that’s FDA-approved for adults with treatment-resistant symptoms. It works differently from traditional antidepressants. While most medications for depression affect serotonin or norepinephrine, Esketamine interacts with the brain’s glutamate system. This difference allows it to bring relief more rapidly than standard options.
We’ve seen how it can help shift the trajectory of someone’s experience. When other medications haven’t worked, Esketamine offers another path—one that’s supported by science and real outcomes.
Who is Esketamine for?
We recommend Esketamine for the treatment of resistant depression in individuals who:
- Are adults diagnosed with Major Depressive Disorder (MDD)
- Have tried two or more types of antidepressants without lasting improvement
- Are open to participating in a supervised treatment program
- Understand and agree to the safety requirements for in-clinic care
Before we move forward with treatment, we conduct a thorough consultation. During that visit, we’ll review your symptoms, past medications, and treatment preferences. If Esketamine is a good fit, we’ll proceed together step by step.
Safety and Oversight Matter
Your safety is one of our highest priorities. Esketamine can cause short-term side effects like dizziness or dissociation. That’s why we monitor you closely each time you receive a dose.
We follow all medical guidance and provide clear expectations so you feel prepared. If you ever have questions or concerns, we’re here to talk and provide reassurance throughout your care.
What We Value in Treatment?
At Gianan Health, we value direct connection, ongoing communication, and dependable care. Spravato treatment is one of the approaches we use when previous antidepressants haven’t worked. But it’s more than just the treatment—it’s about how we deliver it.
We spend time getting to know you, your symptoms, and your goals. We adjust the plan as needed and make sure you have the support you need—not only during the session, but after it too.
Let’s Talk About What Comes Next
If you’ve been living with depression and haven’t found the relief you’re looking for, we encourage you to reach out. Esketamine treatment for depression has helped individuals take a new direction in their care.
Contact us today to learn more or schedule a consultation. We’re here to walk you through the process, answer questions, and help you decide what’s right for you.
At Gianan Health, we know that finding the right path takes time. If Esketamine is part of your next step, we’ll be with you through every phase of that journey.